When a person is insulin resistant, their cells do not respond to a normal secretion of insulin from the pancreas. The pancreas has to work harder and make more insulin than normal than normal to move blood glucose (sugar) out of the blood stream and into cells and tissues.
People with insulin resistance may have different signs and symptoms. Physical symptoms can include skin tags, acanthosis nigricans, weight gain, and hirsutism. Other symptoms can be measured in lab tests including glucose tolerance tests and fasting insulin tests...